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Available lipid emulsions made from soybean or safflower oil are classified as long chain triglyceride (LCT). In contrast, medium chain triglycerides (MCT) have different physical properties and are metabolized by other pathways. Because the medium chain fatty acids are smaller than long-chain fatty acids, they are more water soluble and metabolized faster. To compare of stability the two type of total nutrient admixture (TNA), authors studied in 4 types of formular TNA based on LCT (Intralipose) and MCT/LCT based TNAs had smaller particle sizes when compared with LCT based TNA without significance, but had no significant difference in appearance, pH, hyperoxides and osmolarity. Therefore, We conclude that two types of TNAs were stable for 3 days at room temperature and under refrigeration. In addition to, MCT/LCT (1:1, IntraMCT) at room temperature and under refrigeration (4℃). In results, MCT/LCT based TNAs are more physicochemically stable and available to patients than LCT based TNAs.
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